On the death of Pius III, in 1503, Machiavelli was sent to Rome to watch the election of his successor, and there he saw Cesare Borgia cheated into allowing the choice of the College to fall on Giuliano delle Rovere (Julius II), who was one of the cardinals that had most reason to fear the duke. Machiavelli, when commenting on this election, says that he who thinks new favours will cause great personages to forget old injuries deceives himself. Julius did not rest until he had ruined Cesare. - The Prince, Niccili Machiavelli
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Julius II was also the Pope who commissioned the current St Peter’s Basillica.
Old movie with Charleton Heston as Michaelangelo also features Julius leading a papal army into battle. Not sure if that last was historically accurate.
didn't get that far, but it is interesting to read about Girolamo Savonarola, who burned books and art - Bonfire of the Vanities, preached about morality and could have changed the renaissance if he led better. His fate was death. And art won.