if you're comparing immunologists to bitcoin core devs you're going to have a bad time. biology is a very unexplored in terms of its systems and effects of new drugs on these systems. bitcoin core is very much understood and has very well established domain experts.

I'm ignorant on the subject, why knots, why core, no idea. But after your post I downloaded and installed knots. Guess I'm just an ignorant emotional idiot after all... Good to know for sure.

If you know both great. If you only know one or neither then what? Who do you trust?

I also have qualms about calling a system designed, evolved and run by humans: deterministic.

Trust the one who does not claim to understand complex systems, particularly when mostly unexplored, misunderstood, and/or prone to corrupt incentives.