VC is profit driven, though some of them mentioned to me that they have quota only for non profitable invest, let’s say, for reputation. If I am a VC I don’t see any business model via a client because zap for developer will always be more efficient to make a better product so finally VC backup client won’t win and zap for developer client will have better experience. But other things based on nostr may worth to invest like private relay infrastructure.

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Yeah, that's also a big consideration with Nostr... it's not a protocol that's easy to monetize (different from Bitcoin in that regard). That said, most of VCs that are already in Nostr are very ideological... I know that some of them are already funding developers simply to help sustain contributions; which is amazing.