In the case of data injection schemes like inscriptions it delays blockchain download significantly despite blocks being of the same size. If you have to download the blockchain from scratch and suddenly it takes you a month to complete it on a low tier hardware, when just 2 years ago it took you less than a week, you have two options in front of you: 1) buy additional RAM to speed up the process; or 2) give up running a node entirely. This is a fact, not an opinion. Lower end hardware with 4GB of RAM are effectively useless for running a node. They weren’t in 2022, before the inscription spam wave began.