Long-term plantar fasciitis inflammation issues may be due to circadian disruptions impacting the collagen synthesis to create a different type of collagen that's thicker but not as stretchy Peter Cowan: "Yeah, I do think it's really important to emphasize the circadian stuff because this is something that is completely mainstream now. If you go to PubMed and you look up circadian disruption, basically any issue, you're going to find dozens of papers. Specifically for this collagen synthesis one, though, there's some really good literature on it, and I dug through it. It's not actually that hard to understand. You don't have to know the quantum mechanics or the biophysics even. There's an enzyme called lysyl oxidase that's on a circadian timing mechanism, and then I mentioned MPP earlier […]" Dr. Max Gulhane: "Is that matrix metalloproteinase?" Peter Cowan: "Yeah, exactly. […] The fibroblasts are also on a circadian mechanism so you're getting the effects of basically downgrading of the mitochondrial function in those fibroblasts are very mitochondria dense. But then on the other side you're disrupting the timing, so it's kind of like a double whammy. Then you got the lysyl oxidase factor which is critical in giving that kind of cross-linking that is required for the collagen to become just like the sturdy, stretchy, rope-like, cable-like material. When it's not cross-linked, and the fibroblasts are producing incorrectly, you get a different type of collagen that's thicker but not as stretchy, so it's more prone to breaking when under high loads." Dr. Max Gulhane: "Yeah. So it's compromised. The body is making a tradeoff in the production of these factors to do the best under adverse conditions. And yeah, that sounds plausible to me." Peter Cowan: "I there was an ex-49ers who tweeted. He's like, just for what it's worth I never had plantar fasciitis in my life except for when I was in the 49ers. And plantar fasciitis, you probably can explain, there's like an acute one and a long-term one, there probably is a different technical term, but basically long-term plantar inflammation issues is characterized by a switch I think from collagen type three to type one, or whichever direction. And it's documented in the literature; it's not controversial at all." Peter Cowan with npub19yjldzc98lsesatjncxzgunm8xpdjsr5tva3sjc9ggyqsjh5hedst2unad @ 52:50–55:29 (posted 2026-01-27)

In plantar fasciitis the arch of the foot is usually very tender to palpation and seems quite clearly to be a manifestation of Tension Myositis Syndrome "The pain in _plantar fasciitis_ is located on the bottom of the foot along the length of the arch. Although they are often vague about cause, doctors may ascribe this pain to inflammation. The area is usually very tender to palpation and seems quite clearly to be a manifestation of TMS [Tension Myositis Syndrome]." John E. Sarno, M.D. (1991). _Healing Back Pain: The Mind-Body Connection_, Hachette Book Group, New York, NY, p.117

Dr. Jack Kruse: "I would also ban sunscreen and sunglasses the first day I came in because this is one of the biggest problems. People don't understand. When they hear this, they go, 'But Jack, you're decentralized. You said everything should be available.' Like, I'm okay with it being available; I just don't want you to buy it. Like, I want girls to put the sunglasses on the top of their head or in between their boobs. It looks great there in the pictures. Just don't put it on your eye. You know, if you want sunglasses, sell the [blue-blocking] glasses that you have on your face. That I'm OK with." Max DeMarco: "Yeah. How bad are sunglasses? How much do they disrupt your circadian rhythm and like this clock in the eye?" Dr. Jack Kruse: "I'll make it very simple. Sunglasses are an oncologist's best friend. It's a growth machine for oncology practice. How's that?" Max DeMarco: "So sunglasses slowly kill you?" Dr. Jack Kruse: "Well, sometimes not slowly at all. Sometimes pretty quick, especially if you took the jab." Dr. Jack Kruse with Max DeMarco @ 50:09–51:00 (posted 2025-05-07)

Circadian disruptions are likely to be the biggest contributor overall to the injuries seen across professional football Dr. Max Gulhane: "But if we take a step back and think a bit more about the environment that the players are in. Sure, we're implying or suggesting that being in this [49ers] facility and being exposed to this magnetic field is not ideal, but like what else is happening in the modern athletes' environment that could potentially be impacting healing?" Peter Cowan: "Yeah, I'm glad you asked that because I actually think that circadian disruption is a bigger factor overall. I think that the EMF from the substation is likely kind of like the straw that broke the camel's back for the 49ers, because you're seeing these soft tissue injuries across the league, across all professional sports. […] "But I would just encourage anyone to look at the third article of my series. It's non-controversial circadian mechanisms showing exactly how collagen synthesis and repair is based on timing mechanisms, based on our light exposure. And these football players, when they're not playing games, they're working out indoors under artificial light, and they're staying up watching film reels, analyzing plays when it's dark out. And then they're traveling across multiple time zones every week, practically every week. Then they're playing these games outside with this massive bright lights on them. So that's the circadian stuff. "You can actually see that a lot of players are now starting to use blue blockers, and I've heard that some teams even have like a wind down twilight protocol. I haven't seen actual documented evidence of it but I wouldn't be surprised. This stuff is not really that cutting edge anymore. It's becoming very mainstream. So I think that alone is enough to be causing these issues." Peter Cowan with npub19yjldzc98lsesatjncxzgunm8xpdjsr5tva3sjc9ggyqsjh5hedst2unad @ 45:01–47:10 (posted 2026-01-27)

I don't enjoy cold exposure. Why is that? People with more uncoupled haplotypes tend to benefit more from cold exposure & are more likely to enjoy it. People with more tightly-coupled haplotypes tend to benefit less from cold exposure & are less likely to enjoy it Archie: "I've been resistant to consistent full body sort of cold exposure. I haven't taken to the trend. […] I might sort of finish off lower half of the body with a cold shower occasionally. It does feel refreshing but […] I do my best to avoid that. […] What is the benefit of doing the equivalent of a cold plunge or finishing off with a proper cold shower?" Dr. Jack Kruse: "[…] It's a default reset. […] There's something in physics called the Curie point. It has to do with magnets. OK? When you drop temperature down magnets become more efficient. What else becomes more efficient in terms of electricity? Semiconductors work better in cold. So, if we took your phone and we put it on the hood of the Mercedes-Benz out in the front that's black, you get a temperature warning. We come in here and put it inside the freezer, it will work right away. "Well, I told you that we use semiconductive current in us. So, the benefit of you going in cold water, even if it's a short period of time or a longer period of time, you become more thermally efficient. In other words, you set your electronic state for the proteins in you and the water that surrounds them, because the water that surrounds you is also a semiconductor. In other words, you become much more likely to conduct a semiconductive current which means that you do better. So that's the main reason that you want to do it. "Now I will tell you in different people the effect is different. I'm going to tell you all mammals it's beneficial, but humans are a special case, and I'll explain to you how we found this out. If you have an uncoupled mitochondrial haplotype, which you're kind of close because you're originally from Turkey, Middle East. So, you're probably not as uncoupled as I am. My people are from the 59th latitude. So, I'm very uncoupled. So, when I go in cold water, I get a huge benefit. My mitochondria not only make more water, they release more red light, but they also make a ton of water. That light actually allows me to tan the insides of my body. So, I'm turning on the system that controls melanin inside of me. That's another benefit. "Now, people who are from equatorial Africa who have L0, 1, 2, and 3, these are predominantly people have dark skin. In country you're living in now, those are the bush people. OK? But in Africa, like Nairobi, one degree north, 8,000 ft up, these are the guys that beat everybody in the world in endurance sports. Why? Because they are extremely thermally efficient. But the interesting thing is they don't get the huge benefit out of the cold. How did we find that out? In the Korean War in the United States, when they put people up on the peninsula, you know that North Korea is pretty high latitude. It gets pretty cold. The US military found that black soldiers got frostbite faster than white soldiers, and they couldn't figure out the reason why. It's because they're not thermally able to handle because the amount of melanin that they have on their exteriors. […] "Now, what's the beautiful part of this? People that tend to be heavily melanated tend to be always either at altitude, where there's EMF, or where it's warm. Very rarely are they heavily melanated. There's exceptions; those exceptions are like the original Eskimo." Dr. Jack Kruse with Archie @ 42:08–45:29 & 46:36–46:55 (posted 2026-02-03)

All vaccines are useless as they're based on faulty science. Kids have food allergies & peanut allergies now because we've been vaccinating like crazy this whole time. Anytime we inject a young child with anything, they become hypersensitive to that issue Max DeMarco: "Regarding vaccines in general, […] can you say all vaccines are bad, per se, or is there. . ." Dr. Jack Kruse: "I can, but nobody else wants to hear it. But I think they're all useless. I think they're based on faulty science, and that's the reason they have no controls. It's all by design. And I think centralized doctors, the biggest lie is not statins, it's not cholesterol, it's actually vaccines. I personally think they're all useless. And I didn't have that belief my whole life. I used to believe in the camp that vaccines were wonder drug like penicillin was from Alexander Fleming. But then over my career, I started to notice some very interesting things, and then I went back and looked at the papers. "Like for example, when Andy Wakefield got canceled by the British centralized doctors, I thought it was interesting what he was saying that the MMR vaccine had a lot of problems. So I decided to look into the MMR vaccine. […] The first thing I did is I went back and looked at the tables of when the MMR vaccine, and what the incidence of measles was, and when vaccination came in. The vaccination program came in after measles was already rare. So why the hell did we make a vaccine for a disease that wasn't a problem? "Same thing was true in polio. And the polio idea is what really opened my mind to this because I learned about that when I was a young resident. […] When I realized that there was a big farce behind polio, that not only was some of the people who we were taught in our history books had polio, I'll give you an example. Franklin Delano Roosevelt, FDR, many people sold the idea that he had polio. I'm not convinced that he had polio anymore. I think he may have an autoimmune condition called Guillain-Barré syndrome, for a variety of different reasons. And do I think polio as it was sold through the March of Dimes, FDR, and the industrial military complex through Salk, did we really need a polio vaccine? No. I think the government needed this program, and big pharma needed the program. […] "And then if they look at some of the Nobel prizes that were given for the early vaccination idea, this was done by a French physician where we got the word anaphylaxis. What did actually he show? Anytime we inject a young child with anything, they become hypersensitive to this issue. That's actually where most of the side effects for vaccines come from. Why? because you're fine-tuning the immune system to react against this. "So when pediatricians ask me, 'Why do all these kids have food allergies and peanut allergies now?' It's because we've been vaccinating like crazy this whole time. It goes back to that original Nobel Prize that nobody wants to talk about. Why? Because how you get taught this in medical school is actually built on a curriculum that big pharma pays for and gives to the medical school for free. Where did that idea come from? Rockefeller and the Flexner report." Dr. Jack Kruse with Max DeMarco @ 51:01–53:13 & 54:13–55:04 (posted 2025-05-07)

Dr. Niels Ryberg Finsen won the Nobel Prize in 1901 for the use of UV light in treating tuberculosis pemphigus vulgaris. To this very day, when you have drug-resistant TB, the single best thing that still works is sunlight with UV light Dr. Jack Kruse: "People forget this. Finsen won the Nobel Prize in 1901 for the use of UV light in treating tuberculosis pemphigus vulgaris. This is a bad infectious disease. Do you know to this very day that when you have drug-resistant TB, the single best thing that still works is sunlight with UV light? Even today. But people when I talk to doctors, they don't even know that UV light was given a Nobel Prize before any drug was. It's shocking, you know, when I say this stuff to people because like a young man like you have grown up in a world where, 'Oh no, no, no, penicillin, this and that, these are the greatest things ever.' "And then I casually point out to people, well, everybody seems to know about this polio thing, but they don't know why Jonas Salk and Albert Sabin didn't get a Nobel Prize for that. Why? Because it harmed a lot of people because it was tainted with SV40. OK? And that's the interesting thing. "Everybody knows about Alexander Fleming and penicillin, but penicillin hardly works for anything at all. Why? Because we overuse it and abuse it because we don't understand the decentralized nature of man, and that is the key. And this is the reason why we have so many different things wrong because once the paradigm was stolen from us to centralize medications and centralize our ideas all the things that are found in nature were lost." Dr. Jack Kruse with Max DeMarco @ 58:58–01:00:23 (posted 2025-05-07)

Optimizing the three master hormones (leptin, cortisol & melatonin) affects downstream hormones like estrogen, progesterone & testosterone. Leptin resistance & insulin resistance. Leptin resistance & PCOS. Leptin resistance & infertility. Leptin resistance & hot flashes Sarah Kleiner: "Leptin resistance is a precursor to insulin resistance. It happens first, and that's where a lot of people come to me they're like, 'I've gone through the testing, I'm not insulin resistant, my blood glucose is not diabetic or even pre-diabetic yet, but I'm having all these symptoms.' And the literature is quite extensive around leptin at this point because like I said, it's been discovered in 1994, but there is a tie with leptin resistance and PCOS, leptin resistance and unexplained infertility, leptin resistance and hot flashes. A host of hormone imbalances, which people are usually having these hormone imbalances first, and everyone's like, 'Oh, it's estrogen. Oh, it's progesterone. Oh, it's testosterone.' I'm like, 'Yes, but you don't understand those are downstream hormones.' Right? "We've got leptin, cortisol, melatonin. These are up at the top, and then everything else is underneath, and thyroid as well. If we can optimize leptin, cortisol, melatonin, these three master hormones first, a lot of times these issues with these hormone imbalances, regardless of what it is, they work out. And I think that can be hard for people because they're in this mindset of, 'I have to do this extensive testing. I have to spend all this money to find out if this hormone is low and this hormone is high, or this hormone is you know,' and they get all tied up in these numbers. "When I like to just, it's a lot more simple, and it's a lot cheaper of a route to take to address things in this kind of top-down manner, because again like you said, leptin resistance is a precursor to insulin resistance. There's a ton of literature around insulin resistance as well, especially in regards to hormone imbalances. If these things are not optimized then supplementing exogenous hormones, trying to do specific strategies to raise specific hormones and lower other hormones, it's just kind of like you're chasing your tail, and it could be a big waste of time. "And I know that because that's what I was doing kind of on my fertility journey. It was like, 'Oh, your your DHEA is low, your testosterone is low, this is low, estrogen is a little bit high.' So it's like, 'Let's take this supplement to bring this up, and push this one down,' and like I said, I only would get so far. It would help a little bit, but then I still wasn't getting pregnant, and the weight wasn't coming off. It was just like this big cycle of spending money, and yeah, it was a big waste. Very frustrating." Sarah Kleiner with npub19yjldzc98lsesatjncxzgunm8xpdjsr5tva3sjc9ggyqsjh5hedst2unad @ 20:08–22:58 (posted 2023-10-15)

Struggling with infertility and stubborn weight loss resistance. Discovering leptin, the master circadian signaling hormone. Discovering that circadian practice is absolutely crucial to this whole process. It seemed too simple to be true Dr. Max Gulhane: "In my general practice two of the most common presentations that I see in in my female patients are fertility optimization and just stubborn weight loss resistance. And what […] I really love is how […] you eventually got to the root cause of how to optimize your fertility, and optimizing your fertility was as a side effect of optimizing your biology. […] And I think it's an amazing testament to do a practice that […] you were able to fall pregnant at the age of 42 […] completely naturally. […] So explain from your point of view what this leptin-focused strategy involves. How is that different and more nuanced than simply the diet, or the low carb, or the carnivore-based kind of approach?" Sarah Kleiner: "Yeah, absolutely. I also failed to mention that I lost 30 lbs before I got pregnant. I had talked about that stubborn 20 lbs that I had picked up seemingly out of nowhere. When I implemented these principles I lost 30 pounds and then got pregnant. I don't want people hyperfocused on losing weight if they're trying to optimize fertility, because you don't want to be underweight. You do want […] to be at a healthy weight to be fertile, it's important, so I don't want people to get hyperfocused on that. But I do love to mention that fact that I didn't track, I didn't overexercise, I didn't go crazy with the weight stuff, and it just kind of I lost the weight as a side effect of implementing these things. "But essentially, leptin, it's important, […] it's a master circadian signaling hormone. It impacts your thyroid, it impacts insulin, it impacts your sex hormones. […] Again, it's a master hormone, so it signals all these downstream hormones and impacts them. It even impacts your immune system and bone health, heart health. I mean there so many things that we continue to learn about leptin. It wasn't even discovered until 1994 so there's a lot that we're still learning. "But essentially we want really strong circadian rhythms, and that's one of those things that I always thought was just silly, it's like too simple to be true to go out and look at sunrise every day, and to wear blue blockers after dark. A lot of people dismiss those things, and just want to focus on the food. And then they focus, focus, focus on food, and nothing. They get a little bit, they get a little result, but then they still have lingering issues, maybe thyroid, weight, […] it's still like some of it's coming off, but the rest of it just really isn't. "And so that circadian practice is absolutely crucial to this whole process, so I'm like it you have to do that first. And that involves sunrise, and then the next window is UVA. And people are like, 'How long can I spend out? What's the minimum amount of time?' And I'm like, 'You're looking at it all wrong. I get it. I know people are busy, they have busy lives. But if you go into this thinking like, What's the minimum I can do?' Yeah, I can help you if you have a busy life, and a schedule and all that, but I just I hate when people kind of look at it like, 'What's the minimum I can do?' "I make it a game. What's the maximum you can do? How can you shift your life and shift it? If you really want to heal, you're going to have to shift, and you're going to have to change, and it's a mindset that you're going to have to go into, to like, 'How long can I spend outside in the morning?' And so I think that's really, really crucial for people." Dr. Max Gulhane: "Yeah, and the way I think about circadian biology having come from a predominantly dietary-focused paradigm is coming to an understanding that this is basically the master regulation of our biology. It's like if you don't respect circadian biology you're going to get wrecked. You're going to have a bad time." Sarah Kleiner with Dr. Max Gulhane @ 11:14–16:10 (posted 2023-10-15)

To the ladies in the South with osteoporosis: when you're out having coffee in the morning, take your shoes off, sit on the porch and make like the Sphinx. Look to the east and keep all four of your extremities grounded. Avoid fluoridated water when making your coffee Dr. Jack Kruse: "When you understand how to use purple and red light, that's when your life changes. That's when my life changed. And you know, the really cool thing from my perspective is when you invite me on to do a podcast like this, we jump down the rabbit hole, and we can discuss all the quantum effects and the detailed science. But here's the best part. How hard is it for a patient? It's not hard at all. You know why? "All I do with my ladies in the South that come to me with osteoporosis. So when you're out having your coffee in the morning, I just want you to take your shoes off, sit on the porch and make like the Sphinx. Look to the east and keep all four of your extremities grounded. And they look at me like, 'That's it?' I say, 'Yeah, if you don't mind, when you make your coffee, make sure it's not done with fluoridated water.' "Now, very few of them ask me why, but the ones that do, usually they've been a patient for a while. I tell them why, because what does fluoride fundamentally do to water? It decreases the amount of DC electric current that you make from sunlight. Why? Because fluoride is a dielectric blocker in water. See everything always scales to the same three things, Dan: light, water and magnetism. And that's what a mitochondriac spends most of their time studying." Dr. Jack Kruse with Dr. Dan Pompa and Meredith Dykstra @ 49:06–50:27 (posted 2017-01-13)

See the sunrise in order to renovate heme proteins and to control the efficiency of the Krebs cycle & the urea cycle. Kids with autism tend to love carbs because they can't use the TCA cycle or the urea cycle well. Help them by getting them outside to see the sunrise Dr. Stanton Hom: "Could you share with our audience what you are finding as the most viable ways to generationally help our families experience greater potential?" Dr. Jack Kruse: "[…] Are there basic things that I think everybody can do? Yeah, the number one thing hasn't changed for me in 20 years, you must see the sunrise. And the reason you must see the sunrise is twofold. You have to renovate the heme proteins in your mitochondrial membrane. The heme protein that most people may not know, it's called CCO or cytochrome c oxidase. That makes a special kind of water, not the water comes out of your tap. It's called deuterium-depleted water. Deuterium-depleted water is important for one reason. It actually controls the optical density of light inside of you. So guess what? That's a big deal. What's the other thing that it controls? "It controls the stoichiometry, and I'll explain to you what that word means, the thermodynamic efficiency of the Krebs cycle and the urea cycle. These are the two big cycles that control all these little boxcars that you learn about in biochemistry. Each one of those boxcars has an absorption and emission spectra; that means that light is involved with each step. "So for example, you've probably heard of people talk about ketone bodies and β-hydroxybutyrate. When you talk to Uncle Jack, when you say that, I'm immediately thinking about the light frequencies that those things carry. I just did a podcast with Sabine Hazan who is gastroenterologist is big into the microbiome. And when I talked to her and Alexis Cowan, who's a PhD in biochemistry, I explained to them the same thing is true in the microbiome. What do we know like in autism? Kids in autism have had bifidobacteria completely eliminated. It's almost been an extinction event. So what is the case there? "That tells us that a certain amount of light is not present in these kids with autism. And the process that they went through to get the disease causes this problem in their microbiome. Dysbiosis in autism is not what I would call something that's really well talked about in most areas. But most parents that have kids that are significantly autistic, the one thing they know, those kids tend to love carbohydrates and sweets, and they tend not to like ketones […] or fats. The reason why is because they can't use the TCA cycle or the urea cycle well, because their mitochondria are damaged. And the parents are not being told that they need to take the fucking kids, wake them up, bring them to the sunrise. I don't care if they're screaming and crying, they go nuts. You need to use that because that effectively fixes the big problem, and then we move on from there. "And once you get people on that right path, you get them in that groove, you begin to realize that all the boxcars that are in biochemistry and the urea cycle and TCA cycle, these are all lightsabers that actually get your kid better. And that's really the way I want you to think about it. I don't want to reteach you biochemistry. I don't want to teach you quantum physics, but I'm going to tell you at the base of health and disease is light, water, and magnetism." Dr. Jack Kruse with Dr. Stanton Hom @ 55:58–59:26 (posted 2025-08-01)

259: Decentralized Health: Dr. Jack Kruse on Light, Water, and Freedom – thefuturegen

Heteroplasmy: a measure of mitochondrial inefficiency. If you reduce heteroplasmy, say from 70% to 30%, a disease like diabetes can vanish. Melatonin made by mitochondria gets energized by purple & red light found in AM sun to perform autophagy & apoptosis renovation at night Dr. Jack Kruse: "And when that energy efficiency [of the engine] goes bad, that is heteroplasmy. So in us, what is our engine? The mitochondria. When the energy inefficiency of the mitochondria begins to go up, we have problems. "Now the interesting part that [Doug] Wallace first dug out from his work is that he found that every decade we age, heteroplasmy goes up about 10%. So we now know that aging is tied to a loss of thermodynamic coupling in mitochondria. And then he later figured out in the 1990s and 2000s that as you got a disease like neurodegeneration, or autism, or Leber's optic hereditary neuritis, that the heteroplasmy rate can go up in short periods of time and then the disease manifests. "And then the flip side of that also shows that if you can knock the heteroplasmy, say from 70% to 30%, a disease like diabetes can vanish. And this broke everybody's paradigm. […] Why is it good for people with injury? Because it explains to you that you don't have to take your Ferrari to a mechanic. Your [mechanic] in you is the two change programs called autophagy and apoptosis. Those are what takes out the bad engines. So you have a mechanic inside of you, and it turns out that mechanic works on purple and red light. And what are some of the things that do this? Dopamine, melatonin, GABA. These are things that I think people have heard about, probably but in different contexts than this. And out of those three, the one that's the most important, it appears (based on the latest research we have) is melatonin. Why? "Mitochondria is where most of your melatonin is made. Now, you're going to hear many other doctors come out and tell you it's from the pineal gland. […] We now know that that is […] nonsense. 95% of your melatonin is made in your mitochondria. And when you understand that it controls the two change programs, then it begins to make some sense. Because then you realize, well, this is the mechanic. "And then when you find out a little bit more about melatonin, most people think it's the hormone of darkness when it turns out it's made from an aromatic amino acid that absorbs UV light. You go, wait a minute. UV light's not present at night. So how does this work? […] You look at the aromatic amino acids that melatonin is made out of, and you see the absorption spectra, and it goes between 200 and 400 nm light. So it's clear that you're supposed to be in AM light. And these chemicals, the benzene rings in these aromatic amino acids that make up melatonin, namely tryptophan, they get powered up, meaning they get electronically excited by sunlight. That energy is kept in the benzene rings and in the π electron clouds that are in the chemical structures. […] At night when the stimulus of the light goes away, that changes the electric and magnetic fields. […] "When you change the optical density of something, you change the refractive index of a tissue. It turns out melatonin does that. So when it's dark, the light that's stored on those electrons gets released to the tissues, and that's when physiologic work can be done. That's actually when the renovation is happening to your colony of mitochondrial DNA. That's really how it fundamentally goes. And then when you understand the way that light enters us, the two primary ways are through your eyes and your skin." Dr. Jack Kruse with Dr. Stanton Hom @ 13:38–18:11 (posted 2025-08-01)

259: Decentralized Health: Dr. Jack Kruse on Light, Water, and Freedom – thefuturegen

How cold thermogenesis (CT) improves mitochondrial functioning. CT brings the respiratory proteins closer together. The closer the respiratory proteins are together the better the quantum tunneling is Matt Maruca: "When it comes to the CT series and the CT benefit that humans (and essentially all mammals) can get, does that initially descend from the extinction event?" Dr. Jack Kruse: "No, it starts immediately 3.8 billion years ago about the story I told you about redox chemistry. It turns out redox chemistry always works better when it's cooler. […] Remember what I told you that's in Nick Lane's book, that the closer the respiratory proteins are together the better the quantum tunneling is. And when the angstrom is split apart, it's a logarithmic effect; it's not a linear effect. So you lose energy production tremendously. So what does cold thermogenesis functionally do to the respiratory proteins, which is cytochrome I, II, III, IV, and the ATPase? It brings them closer together. You want that that whole complex from I through V to be within 48 to 60 angstroms. We know that from new science that's been done by people who are mitochondriacs. It turns out when you have diseases and heteroplasmy is higher they're spread out, and that's exactly what the stimulus is for apoptosis. Most people know that apoptosis is controlled by cytochrome IV. What happens is there's a whole sequence. . ." Matt Maruca: "I don't think most people actually know that [laughs]." Dr. Jack Kruse: "Well I mean they should, because what happens is the mitochondria swells, and the swelling opens up mitochondrial pores. One of those chemicals that people probably have heard is cardiolipin, and what does that do? It basically takes apart cytochrome c oxidase, and it leads to a cascade of events that's called apoptosis. Now it doesn't go fully, it can lead to fission, it can lead to fusion, there's a lot of different things that it can lead to. But that's functionally how it happens. "But it tells you again we're back to quantum thermodynamics. Most people don't realize that the tunneling of electrons requires a precise distance between the two. I've taught people ad nauseam, Matt, you remember how many times that I show you the chemical structure of chlorophyll and hemoglobin when you look at them they're identical. The atomic spacing is identical the only difference is that there's magnesium in the center of chlorophyll, and there's iron in the center of your red blood cell hemoglobin. And why is that a big difference? Magnesium is atomic number 12, iron is atomic number 26. What does that mean? You got 14 more electrons. What does that mean? You get more light, so you can be more complex. "Now you're back to the light diet again. That's how this works. Everything about you is light, and you know what? We got to get people to understand it is about light." Dr. Jack Kruse with Matt Maruca @ 45:59–49:04 (posted 2020-12-16)

If you sit in an electric car with a TriField TF2 meter you'll never want to sit in one again because it literally blows up the meter, flatlines it at max, on both the magnetic & the electric front. Irradiating your sex organs Shawn Stevenson: "OK, I'm going to do it. This is controversial. I want to ask you about electric cars." Dr. Alexis Cowan: "Oh, god." Shawn Stevenson: "Is there an issue? Because again, just thinking about this stuff because it's invisible and it's a big part of our culture now. Could our health be at risk when we're sitting in an electric vehicle or even a hybrid vehicle for long stints of time? I'm just going to pass it to you. I'm curious." Dr. Alexis Cowan: "Please. Yeah. I'm thankful that you went there because part of Becker's really important work was not only on the radio frequency front, but also on other forms of non-native EMFs, including non-native electric fields and magnetic fields. So, when we're talking about electric vehicles, we're really talking about these electric and magnetic fields. There are radio frequencies as well. The cars are Bluetooth laden, they're communicating with towers and they have all these modern conveniences, but that comes at a cost in my opinion. "If you just simply get like a TriField TF2 meter, they're like $200 on Amazon, and you turn that thing on and you go sit in an electric car, you'll never want to sit in one again because it literally blows up the meter, flatlines it at max, on both the magnetic and the electric front. So when it comes to batteries in general, they make a very strong magnetic field. And interestingly actually Becker's work in _Cross Currents_ and _The Body Electric_ he highlights the effects on growth, basically creating apparent growth or changing cell cycles from magnetic fields and electric fields. Even the AC power grid itself creates non-native EMFs in the form of dirty electricity of these non-native electric fields. So, whenever you're plugging something into a wall, that thing is going to have some level of detectable electric field coming coming off of it. "Now again, proximity is king when it comes to this. So, the closer you are, the stronger it's going to be. When it comes to electric vehicles, in particular, if you're sitting on the driver's side or the passenger side in the front seat, you're getting bombed compared to somebody in the back seat. They're getting a little bit less, but it's still quite high. And I believe in like Teslas and a lot of the popular electric cars, the battery is basically like right underneath the driver's seat, irradiating your sex organs and just going basically straight up your body. "So they're a huge no for me. I will never drive an electric car. Like you couldn't pay me to buy an electric car or to use one. Actually I remember the first time I sat in one, I got like this massive migraine and that was actually about a year, year and a half after I fell down the quantum and circadian biology rabbit hole. "And one thing that people will notice when they start engaging in these practices, when they start getting out at sunrise or first thing in the morning when they wake up, getting some midday sun, blocking blue light at night, only using red light, candle light, getting dark darkness in the evening, you start to build back your sensitivity." Dr. Alexis Cowan with Shawn Stevenson @ 45:00–47:51 (posted 2025-11-13)

DHA needs the shorter frequency light to run the main body clock in the SCN faster than the peripheral clocks. LEDs are missing the shorter frequency light. LEDs also have a huge spike in the blue range, impacting the melanopsin receptor. Incandescents mimic the sun closest Dr. Jack Kruse: "The key to DHA is you need to know that you need more of it in the eye to run this clock faster because what does DHA fundamentally do? It turns sunlight into a DC electric current. […] It's the big time key in this system here between the retina and the leptin receptor, and that whole key is the retinal hypothalamic tract. "And for those listeners who want to learn more about how incredibly important it is to know about this, there's a famous guy who used to be Walt Disney's time-lapse photographer. His name is John Ott. […] You need to read his book called _Health and Light_. This guy was incredible. He wasn't a scientist, but he was an observer. And I always tell people that humans are really good to see, but they're not good observers. This guy was unbelievable in his observations utilizing time-lapse photography, and he actually postulated that the problem with most diseases came from this defect in the central retinal pathway. And he brought this information to several different doctors. Some of them listened to him, but of course the bigwigs in, like, ophthalmology, they thought he was completely crazy. "And it turns out he's been now vindicated. Every journal you pick up now about chronobiology talks about the central retinal pathway. And guess what the central retinal pathway connects to, Dan, in the retina? The melanopsin receptor, which runs 435 to 465 in the retina. That's strongly in the blue range. "And if any of your members want to really see the true devastating effect of light, I would tell you, go look at my Ubiquination 24 blog post. I put three spectrums up of incandescents, that's the bulb behind me, fluorescents and LEDs. And you'll notice that fluorescents have a huge spike right at 465. You'll also know that LEDs have a huge spike there. The key thing is they have no red. "Incandescents mimic the sun closest. Now, is it close enough to keep you extremely healthy? In my opinion, no, but did it do a way better job for the first 65 to 70 years in the 20th century? Absolutely. And that's the reason why Neolithic diseases didn't begin to explode until 1960 and 1970. What did we do? The key thing is when you subtract out the UV purple and the IR red, what is the bulb called? It's called energy efficient. Why? Because you do. You use less electricity. "It goes to the story that you just asked me, Dan, about DHA. The key is, you need the shorter frequency lights to run this clock faster, and DHA is the chemical that does it." Dr. Jack Kruse with Dr. Dan Pompa and Meredith Dykstra @ 42:47–45:53 (posted 2017-01-13)

LED bulbs have a huge blue spike. The blue spike can be used to control people through the dopamine pathway. Melanin breaks down into dopamine. If you open the blood-brain barrier dopamine floods the brain and it causes brain damage Dr. Jack Kruse: "[2011 is] magically when Obama says we're going to get rid of incandescent bulbs; we're going to go to LEDs. What do they find out? Because LED bulbs remove UV and red light have a huge blue spike. It turns out the blue spike can actually be used to control people through the dopamine pathway. How does that work? [...] "Melanin breaks down into dopamine. If you open the blood-brain barrier dopamine floods the brain and it causes brain damage. Anybody who's a health care practitioner, I guarantee when Kevin listens to this he'll understand it, knows that when we use dopamine in an ICU setting we have to be extremely careful with it when we're trying to elevate their blood pressure, because a low dose, a medium dose, or high dose can kill you. When people are in the ICU, they're around electromagnetic devices, this is the reason why. Because we're flooding their brain with dopamine, we're flooding their brain with serotonin. There's even something called the serotonin syndrome that y'all can look up and fact check Uncle Jack. This is the key things that Allen Frey finds out for DARPA." Dr. Jack Kruse with Marty Bent @ 28:28–29:41 (posted 2025-03-04)

How Hashimoto's impaired Sheryl's cognition. The mechanism Becker found to regenerate bone also regenerates other tissue. Reconnect with nature. Sunlight! Outside! That's how you regenerate the melanin sheets. Nature made us to be addicted to the healing sun Sheryl Utal: "I have been working in every possible way to elevate my consciousness, and optimize the time that I do have here for about the last 15 years, and your teachings have been a big part of that. […] I never really thought about my condition [Hashimoto's] being a TBI, but when you say that it makes so much sense to me, because I couldn't think at that time. I had cognitive impairment and it was really difficult. I had to dig deep for the will to fight for my life essentially, and to fight for my health and my well-being." Dr. Jack Kruse: "People don't understand that the leptin-melanocortin pathway, the real basics, is when you understand that those first order neurons go to the SCN and they go to the habenular nucleus. That is the reason you can't think, because anything distal to those tracts, and in your case, what's distal to the SCN tract? Your hypothalamus. That's where your thyroid problem is. What's distal to the habenular nucleus? Your frontal lobes. That's how you think. That's your new real estate that turned you to human from chimp. So what you just said totally makes sense. […] "What you need to realize what you profit from is actually nature. […] Read what Becker really found in bone regeneration. He found that the smallest ever electric current regenerates bone, doesn't leave a scar. So any disease you come to me with, but magically you know what happens, they're like, 'Oh well, that's just bone.' I'm like, 'OK. How about at the end of his career he was actually able to regenerate fingertips in a three-year-old who cut 'em off. And not only was it the the tissue, it was the bone, and the sensation. Everything came back.' "I just had one of my members ask me this question. […] 'Hey, Jack. I've got periodontal disease and they think I need to have periodontal grafts and this and that. What should I do?' And my answer was, 'How about you read the fucking blogs.' Because how do you regenerate your periodontal tissue? The same way Becker did! But they don't get it. It's reconnecting with nature, and it is that simple. It's the reason I'm here where I am, out of, how shall I say, the theater that is built in the United States to control you. There's not towers all the way around me. OK? […] I do have satellites above me, but thankfully I have a roof with grass on it that keeps Elon Musk at bay and keeps DARPA at bay. "So I guess what I'm trying to explain to people to become more fully conscious you need to understand what the key points are in the lessons that someone delivers to you, and no, don't get lost in the fluff. "But I'm telling you that number one thing that Becker found is huge, just like I told Andrew […] that every single cell releases ultraweak UV light. Well ask yourself why. It turns out that's what turns POMC on. That's how you regenerate your damn melanin sheets. What makes the water? Sunlight! Outside! That's the reason why β-endorphin is part of POMC. Nature told me the freaking answer 25 years ago. You are addicted to be in sunlight. We make opiates when we're in the sun. Like I don't know how big a telegraph that should be to everybody, but guess what? I've been saying it, and people still look at me like I'm crazy. And every time they put those Apple things in their ears, or they're watching a virtual reality thing, they have no idea that they just destroyed every single peptide that comes out of POMC." Dr. Jack Kruse with Sheryl Utal @ 01:03:51–01:09:14 (posted 2025-03-08)

Fat adaptation occurs when the inner mitochondrial membrane oscillates at 100 Hz. Cancers occur when your mitochondria cannot oscillate at a 100 Hz. We need to teach people how to engage autophagy, apoptosis, & biogenesis to fix their mitochondria Dr. Jack Kruse: "Fat adaptation has nothing to do with the fuel that you put in. You know what fat adaptation has to do with? […] The respiratory proteins stretched out. And guess who taught us that? Doug Wallace. And here's the key that we need to understand. When you get somebody, like say in one of my patients in the office has brain cancer. It doesn't mean that eating sugar is what caused this problem. It means eating sugar right now for that patient is a real problem, but to demonize sugar is the wrong thing. You know what the problem is? "That person has mitochondria that is senescent, meaning they're stretched out, their respiratory proteins are at 60 angstroms, they're no longer at 36. So even when you give them the proper fuels, they can't use it. So they're a Nissan Sentra blowing black smoke. They're not fat adapted. And what did Wallace teach us? "Fat adaptation occurs when the inner mitochondrial membrane oscillates at 100 Hz. Well guess what? That means that all cancers are situations where your mitochondria cannot oscillate at 100 Hz, and that's the real problem. So the key thing is to take those senescent mitochondria and fix them. In other words, here's the beautiful thing. "We come with change programs in our body. We need to teach people how to engage autophagy, apoptosis, mitochondrial biogenesis, or what we call mitophagy, and then we can get to the business of fixing it. Where Seyfried is right is it is a mitochondrial problem, not a nuclear problem. And for that issue I am always on his train. But when he starts down this glucose is bad thing, I'm sorry, if glucose is bad, everybody that lives on the equator should be dead. And that's not true. And the reason it's not true is because they have huge quantum yield from their environment. The problem is where he is at Pittsburgh, where Meredith is, those people eat bananas at the 42nd latitude and they do get brain cancer. And people who don't think deep enough blame sugar instead of realizing there's other things that are causing this problem. That's how we're going to solve the problem." Dr. Jack Kruse with Dr. Dan Pompa and Meredith Dykstra @ 58:59–01:01:11 (posted 2017-01-13)

Circadian mismatches are the cause of leaky gut. If you live in an environment where there's no UV light then sugar is a problem. Eating a banana on Dec 23 in Pittsburgh causes a circadian mismatch. If you live around the equator you can eat sugar without problems Meredith Dykstra: "But something that really struck me, I thought it was so interesting when you were talking about food as information as we know, but that if we eat foods that aren't naturally in our environment, that it's a circadian mismatch. So I'm thinking, okay, I'm here in Pittsburgh and I'm. . ." Dr. Jack Kruse: "Don't eat any bananas." Meredith Dykstra: "Right. Well, I don't do bananas because of the sugar content, typically, but I'm thinking well I just ate them." Dr. Jack Kruse: "That's not the reason why. […] I'm glad you brought this up and I don't mean to interrupt you, but when you say this, I think this is going to be a huge benefit for people. I got to get you past. […] "Sugar is not the problem. You know why sugar is the problem? Because you're designed to eat sugar when there's UV light in your environment. Guess what? If you live in an environment where there's no UV light then sugar is a problem. But guess what? We have a lot of data from people that live around the equator that they can eat sugar and it doesn't cause problems that it causes us. But guess what? "Pittsburgh's at the 42nd latitude. On December 23rd, my dear, you're only going to see about eight to eight and a half hours of sunlight. And the only time you're going to get even a whisper UV is right around solar noon, which in your place is around 12:50 to 01:00 right now. So guess what? "You have no business eating very much carbohydrates at this time because of your latitude. And to take this further back, I want you to think about the Inuits because that's the one tribe that lives even north of you. The only carbohydrates they ate is usually when they grew locally. And see the problem is we control our environment now. And just because it is available in Whole Foods in Pittsburgh doesn't mean you should eat it. Why? Because what's the other part of the system? "The other part of the system that we spent a lot of time talking about was the eye and how it's sampling the sunlight. So the gut surface also needs to be yoked to that, and it is. And see, many of these alternative practitioners talk about leaky gut and they drive me nuts because they fundamentally don't realize that circadian mismatches are the cause of leaky gut, and it's not by most of the stuff that they believe. So when you eat a banana in Pittsburgh, you effectively cause a leaky gut because of a circadian mismatch." Dr. Jack Kruse with Dr. Dan Pompa and Meredith Dykstra @ 55:13–57:32 (posted 2017-01-13)

Embrace viruses as they allow us to innovate. Does your doctor start with, "Go outside, get fresh air, good water, reasonable sun?" You have a doctor inside you that works if you get out of its way. Sunglasses disrupts your ability to make needed hormones. 10 meds at age 50 Dr. Jack Kruse: "I'm going to tell you that viruses are actually something to embrace. That's actually how we build our genes as humans. When I tell people that their heads explode but it's true. 98% of the human genome […] are made from HERV viruses. Those are viruses that are retroviruses. […] So guess what? It means that mother nature shuffles the deck. We keep collecting viruses and that allows us to innovate solutions through the chaos, the butterfly effect, that we affect nature. "The problem is, can we create solutions when we live an indoor life? Just remember 1910 or the beginning of the 20th century when the Flexner report was first come out, nine out of 10 people worked outside. Today, 120 years later, 98% of people now work indoors. Has your doctor ever stopped to ask you that question? […] "If your doctor doesn't start with going outside and getting fresh air, good water, reasonable sun, then you have no business listening to them. […] "If […] your husband […] planted an orange tree in the backyard and your kids came out and put water and nutrients in the ground, after say, six months, would we get oranges? Turns out we would, right? But what happens if Jason […] comes around and puts a tarp over that tree? Are we going to get any oranges? […] "How smart is it to put contact lenses, eyeglasses, or sunglasses in front of my eyes, when I do know that there's these things called optic nerves that connect to my brain and my pituitary gland, and my pituitary gland makes all these hormones. Am I going to make all the hormones naturally? Is this the reason why people in California, Chicago, and New York have to spend $250,000 at the fertility clinic to have babies now? Is this the reason why kids don't want to have sex anymore because they're constantly checking their phone 150 times a day and that blue light destroys their circadian biology? […] "That's your job to ask, 'Is the digital babysitter that you bought your kids the real problem?' You want to blame it on your kids but you know what? More often than not it turns out it's the parents' decision around the choices in the kids environment that are important. […] "You have 3.8 billion years of quantum randomized controlled clinical trials going on in you. You have a doctor inside your head and your body that works if you get out of its way. Do you want to know what the single biggest problem is for most modern humans? They have this quantum computer in their head called the brain that allows them to break all of nature's laws, and they do it below their own perception. I told you just wearing clothes or putting contacts or glasses on are some of those examples. […] "Are we really surviving, are we really thriving, or are we sick and we're tethered to some big solution? I mean the last data I saw is a 50 year old the United States is tethered to a minimum of 10 medicines. To me that's preposterous." Dr. Jack Kruse @ 45:25–46:49, 48:15–50:07, 51:06–51:38 & 52:24–52:41 (posted 2020-11-13)