#Tau pathology is a common denominator for #neurodegenerative diseases such as #Alzheimer’s disease or frontotemporal dementia, but selectively targeting toxic tau remains a challenge. Here, Gaikwad et al. developed a conformation-specific antibody for tau and demonstrated selective targeting of toxic tau aggregates in patient-derived tissue and tau oligomers in vitro.


2 Medical News
Nasal tau #immunotherapy clears intracellular #tau pathology and improves cognitive functions in aged tauopathy mice
Editor’s summaryTau pathology is a common denominator for neurodegenerative diseases such as Alzheimer’s disease or frontotemporal dementia, bu...
