By first principle, dose of anything matters. You (proverbial you) get a script for a certain dosage of mg for a medication. If it’s too strong, there’s adverse effects. If it’s too weak, it’s ineffective. By definition, sugar and vegetable oils are drugs. They are extracted from their natural state and highly concentrated for consumption. We get cocaine from coca plant. We get heroin poppy seed plants. We get sugar from beets, sugar cane, etc. We get vegetable oil from canola, sunflower, safflower, etc. By first principle and definition, sugar and vegetable oils are drugs in which dosage matters. You can blame either one for a dearth of adverse metabolic diseases or symptoms.