I've stopped using it as my daily driver. I found version upgrades required quite an investment in time and their perfered approach to declarative config kind of sucks. I now use nixos and i try and compartmentalise as much as possible. https://github.com/CertainLach/nixos-qubes looked really promising and it looked like they were making a lot of progress really quickly but they seem to have abandoned the project 9 months ago.
