Changing the profile of the tail risks you're taking on is always material and practical. Whether that profile is right for you just depends.
When you absolutely need to make a bitcoin transaction, and you need that transaction to get mined, self custody is the only way to guarantee you can make that happen.
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I don't run into a lot of normative American grown ups that absolutely must make a Bitcoin transaction at any given time.
Changing the goalposts are we? That's the actual benefit of self custody, believe it or not.