We have a very close farmer friend & wife who have been a neighbor at farmers markets with us for 20 years. He is younger, has two children of whom we are very fond. He once had three. His eldest shot himself at the age of 10 with one of the family guns. They always went fishing, hog hunting, foraging for mushrooms, milling wood, and the boy was very comfortable in the mill, woods, around guns, and an accomplished tennis player, with many reasons to live. She is native Peruvian, taking regular trips back to Peru, so the children know their antecedents in that country. Both parents were crushed, devastated at the child’s death, becoming hollow shells of themselves for years. He finally went to Costa Rica, and self-prescribed ayahuasca, with a group of experienced enthusiasts, deep in the rainforest, to hopefully release him from his emotional spiral, and help him process the pain. He wanted be more present for his young children, who were suffering, too, (as they loved their elder brother very much, and they did not understand why he would choose to leave them). Our friend said it was an intense, spiritual experience, and definitely helpful, but not for someone as fragile as his wife (who was, piled on with suffering at that time, recovering from breast cancer). He said it was not for everyone, but it helped him. This may have little to do with a nutritional cleanse, but I felt this is a sort of cleanse, too.