"DHA works with something called the RXR and the VDR receptor. Everybody's heard about the VDR receptor; that's the vitamin D receptor. Well the RXR receptor is the vitamin A receptor. […]
"Turns out that all opsins in the body, and melanopsin happens to be a blue light detector, are bound to vitamin A. So this is the control mechanism of how this clock mechanism works everywhere in your body.
"If you break off the vitamin A from melanopsin, it destroys photoreceptors in your body. That's how we destroy melatonin. It's how we destroy DHA. It's how we destroy the [Bazan] short and the long loop.
"This is the basis of how #leptin resistance occurs. When that long loop is broken, that's how you break it in the liver. That's called leptin resistance part 2; I've got a blog about that from over 10 years ago.
"When you start to see all these pieces and parts, you begin to realize, hey man, this clock mechanism in the eye controls all these timing issues everywhere else in the cell. Then you realize that this all goes back to circadian biology.
"Then you realize it's not about food and exercise. It's about light and dark. It's about how well we can tell time. It's about the light we live under. It's about how accurate do we live a species-directed life. And unfortunately most of us don't do a good job of that anymore." — Dr. Jack Kruse with Steve Stavs @ 01:00:05 – 01:01:49
"Because you always hear people talk about dopamine, but they really don't break it down for you so you understand it. People who are depressed, who are gonna kill themselves, or who are fat, or do drugs, those are low dopamine people, those are the ones we always talk about.
"But you know who we never talk about? The people at high dopamine, who have the high spikes, who are those people? Those are the people with schizophrenia. Still a mental disease. So the point that I'm trying to make to you: it's not that all mental disease is low dopamine. Most of them are, but some of them are high dopamine.
"Then there's the part in the middle which is the Jackson Pollock guys, who painted in fractals. Why? Because when dopamine is not optimized, you see the world instead of being smooth, like it is right now, you see it in still shots. That's what the fractal nature is. And that's actually tied to the light that we use to do this. It's a dopamine effect tied to UV-A light." — Dr. Jack Kruse on the Align Podcast @ 19:10 – 20:04
"Water touches every square surface area of every protein in your body. The number one protein your body's collagen. So water does have a memory. The memory is tied to topology. What is topology? It's the study of size and shape changes.
"So it turns out when light hits water it changes the size and shape of the hydrogen bonding networks that surround each protein. That information is transmitted to the protein and back. It's a bi-directional device.
"So memory is coded for in water. Most people think that memory is code for in the central nervous system, like in the brain, or in parts of the brain. But you happen to be talking to neurosurgeon who's taking large parts of people's brains out, and it doesn't affect their memory at all." — Dr. Jack Kruse on the Align Podcast @ 17:57 – 18:48
"Trees are wonderful. In fact the best place you can sit for #mitochondrial health is under a #tree in the #sunlight, because you're protected from the short wavelengths by the the canopy of the tree, and almost all of the #infrared will be bounced down to you […] Tree leaves are incredibly efficient infrared scatterers, and as you've seen in infrared photographs the tree canopy is brilliantly white in the infrared." — Robert Fosbury, PhD with Max Gulhane MD @ 01:26:56 – 01:27:26
"[…] it's in the literature […] that if you change mitochondrial functioning in one part of the body, other mitochondria in different parts of the body respond. […] It's call the abscopal effect. And one of the consequences is if we expose a part of your body to red light, say, your back, 24 hours later we start to get an improvement in vision.
"That abscopal effect has been very well known in limited communities like radiologists. The argument is that mitochondria regulate aging, and you can't have your liver aging a different rate from your left foot. So there has to be a harmonization of mitochondrial function.
"And that's great for us because if we want to improve vision in an ophthalmic clinic, we don't necessarily have to shine something into anybody's eye. That's quite a dramatic finding. […]
"But I'm going to reiterate the point that Scott [Zimmerman] and Bob [Fosbury] have made: you can go and get a red light, and I can tell you what kind of red lights and where you get them. It's actually better just to walk out on a sunny day and spend an hour walking around. That's probably as good as everything else. You're back in your evolutionary niche doing that." — Glen Jeffery, PhD with Roger Seheult, MD; Scott Zimmerman; and Robert Fosbury, PhD @ 40:15 – 42:29
Episode 93. Live discussion on the effects of light on health and medicine.
Roger Seheult, MD of Medcram, talks about the effects of light on health and medicine, in this live Twitter/X Spaces discussion with Scott Zimmerma...
Owen Sheasby: "I understand that the little mammals after the KT event were making light inside of them. But how does that negate their need for food?"
Dr. Jack Kruse: "It doesn't negate their need for food. They are actually able to make food from the POMC gene. The POMC gene has another part of it […] called ACTH […] That's the precursor for cortisol. […] when you give somebody cortisol, what does it make in their body?"
Owen Sheasby: "Raise glucose and insulin."
Dr. Jack Kruse: "There you go. So you're able to actually make glucose directly from light. […] The POMC gene is actually tied to animal photosynthesis. […] every mammal has POMC in them. […] humans do. […] And […] putting on #LED light alone […] raises blood #glucose and it raises #insulin. […]
"What do you know about high glucose and high insulin? Shrinks your #brain. What do you know about the mammals that were present at the KT event? Were they were they mammals that had Ferrari engines in their head?"
Owen Sheasby: "No, little things."
Dr. Jack Kruse: "Right. See, they were different mammals than we are today. So what does that tell you about mammals today, that are living under light that is like the KT event, blocking the sun?"
Owen Sheasby: "They're shrinking their brain."
Dr. Jack Kruse: "There you go, bro. Now you understand why #Alzheimer's, #Parkinson's, and #neurodegeneration are playing the role that they're playing today. You're beginning to understand the flip side of the story.
"But remember the original story for the mammals was this allowed them to survive a poor light environment while the dinosaurs were dying, because there was no #sunlight there. They could live off a poorly lit environment, because they could make enough glucose to survive until photosynthesis came back."
— Dr. Jack Kruse with Owen Sheasby @ 01:42:10 – 01:44:45
"But if I was a wrestler, and I'm going to be very honest with you. What I would do:
"I would move to a tropical environment. Train outside. I would never wear shoes. I would probably wear a Kiniki or a Cooltan, you know, bikini shorts. I'd have the best tan that's natural in the world. I wouldn't take any supplements.
"I would completely stay away from conventional thinking. I may talk to those trainers, but I'm going to maximize my training in a totally decentralized way. I'm going to commit to doing that for one year, and then you check your results.
"And I think, I'm at least very confident in telling you this, that you're going to do a lot better. But the single most important thing is what I've already told you on this podcast:
"When the sun rises, you rise. When the sun sets, you set. That is axiomatic. You break that, I don't care what else you do. You got to have proper circadian timing in that clock in your eye. It's called the suprachiasmatic nucleus. That controls every other molecular clock in your body. If you don't have that, you ain't gonna to be optimal, no matter what anybody tells you."
— Dr. Jack Kruse on the Wrestling Mindset podcast @ 01:02:24 – 01:03:37