seems like we have reached the point of adoption where people do gym workout videos and give financial advice
Byzantine
byzantine@stacker.news
npub1t5wc...6dke
even the byzantine empire fell
seems like @Zapstore is going to be very important going forward
seems like a lot of vocal people are stating that tariffs are not increasing prices.
try and buy a japanese made car. they are all increasing msrp.
here is an example of subaru.
https://www.cars.com/articles/how-much-did-subaru-prices-increase-after-tariffs-went-into-effect-510259/
american's will pay for the tariffs and this will usher in stagflation
i think we will soon move into a world where the counter culture movement of "high tech off-liners" starts to go mainstream.
even though many of the young people consume tic tok they want to stay intensely private
prediction: the liabilities off LLMs suggesting something terrible and causing a fatal unintended flaw in a mission critical workflow will one day cause lawsuits of such a grand scale that proprietary "AIs" to be financially liable just like self driving cars.
The only way forward will be usage of open source LLMs with no ULAs attached to them.
The only multi decade financial benefits will accrue to infrastructure providers in the AI boom
Great chart by @Great Ghee
novel: "Flybot" by Dennis E. Taylor is good like a Daniel Suarez novel
putting 39% tarrifs on swiss gold bars is going to cause an epic gold price revaluation on trapped US supply.
then when gold reprices to $5k+ the US will revalue the treasury's gold holdings and use that revaluation to buy spot bitcoin in a budget neutral way.
Stacker News
Gold Market 'Upended' On Report Of US Tariffs On Swiss Bullion \ stacker news ~econ
Sorry Peter Schiff [4 comments]
here is a list of all the studies showing harms of linoleic acid (primary omega 6 in seed oils)
Human studies
1. Ramsden CE, Zamora D, Leelarthaepin B, Majchrzak-Hong SF, Faurot KR, Suchindran CM, et al. Use of dietary linoleic acid for secondary prevention of coronary heart disease and death: evaluation of recovered data from the Sydney Diet Heart Study and updated meta-analysis. BMJ. 2013;346:e8707. doi:10.1136/bmj.e8707
2. Ramsden CE, Zamora D, Majchrzak-Hong S, Faurot KR, Broste SK, Frantz RP, et al. Re-evaluation of the traditional diet-heart hypothesis: analysis of recovered data from Minnesota Coronary Experiment (1968-73). JAMA Cardiol. 2016;1(3):294–302. doi:10.1001/jamacardio.2016.1313
3. Rett BS, Whelan J. Increasing dietary linoleic acid does not increase tissue arachidonic acid or inflammatory eicosanoids in healthy subjects: a randomized controlled trial. Br J Nutr. 2009;102(10):1515–25. doi:10.1017/S0007114509992980
4. Wood LG, Gibson PG, Garg ML. Circulating biomarkers are related to dietary fat intake, but not atopy or asthma, in adults. Lipids. 2004;39(11):1071–6. doi:10.1007/s11745-004-1025-3
5. Baticic L, Denham JM, Knoke JD, et al. Dietary ω-6 PUFA and systemic oxidant stress: a controlled trial. Prostaglandins Leukot Essent Fatty Acids. 2009;81(5-6):355–63. doi:10.1016/j.plefa.2009.09.004
6. Sathivasekaran S, Malathi S, Haripriyal S, Ramya K, Palanichamy R. Dietary ω-6 polyunsaturated fatty acid intake and cardiometabolic markers among Indian urban adults. Eur J Clin Nutr. 2021;75(8):1248–55. doi:10.1038/s41430-020-00789-4
7. Marklund M, Wu JHY, Imamura F, et al. Biomarkers of dietary linoleic acid and risk of incident cardiovascular disease: results from pooled cohort studies of 60 000 adults. J Intern Med. 2019;286(1):71–82. doi:10.1111/joim.12898
8. Harcombe Z, Baker JS, DiNicolantonio JJ, Grace F, Davies B. Evidence from randomised controlled trials does not support current dietary fat guidelines: a systematic review and meta-analysis. Open Heart. 2015;2(1):e000273. doi:10.1136/openhrt-2014-000273
9. Mozaffarian D, Ascherio A, Hu FB, et al. Interplay between different polyunsaturated fatty acids and risk of coronary heart disease in men. J Lipid Res. 2004;45(2):351–4. doi:10.1194/jlr.M300292-JLR200
10. Brown WVB, Knopp RH. Effects of corn oil on sudden cardiac death. Lancet. 1993;342(8876):1043–4. doi:10.1016/0140-6736(93)92433-S
Animal / cell studies
11. Yang J, Nakada T, Suzuki K, et al. Dietary safflower oil supplementation increases oxidative stress markers and impairs glucose homeostasis in mice. J Nutr Sci Vitaminol. 2017;63(6):453–61. doi:10.3177/jnsv.63.453
12. Deol P, Fekete E, Woodrow J, et al. Safflower oil‐rich high‐fat diet induces obesity, inflammation, and insulin resistance in mice. PLOS ONE. 2015;10(10):e0139441. doi:10.1371/journal.pone.0139441
13. Tateyama Y, Yamamoto M, Matsumoto M. High-linoleic safflower oil induces endotoxemia and gut dysbiosis in Wistar rats. J Nutr Sci Vitaminol. 2022;68(4):304–11. doi:10.3177/jnsv.68.304
14. Nishimukai M, Yamaguchi R, Hara H, et al. Linoleic acid-enriched diet suppresses hepatic autophagy via lipid peroxidation in mice. BBA Mol Basis Dis. 2020;1866(3):165627. doi:10.1016/j.bbadis.2020.165627
15. Liu S, Li Y, Sun Y, et al. Linoleic acid induces DNA damage and suppresses insulin secretion in beta cells. Cell Rep. 2023;42(4):112315. doi:10.1016/j.celrep.2023.112315
16. Yang J, Sato H, Wang D, Wang Y. Volatile aldehydes from commercial cooking oil aerosols enhance lung-cell oxidative injury. J Agric Food Chem. 2021;69(46):13715–24. doi:10.1021/acs.jafc.1c03889
17. Halade GV, Rahman MM, Fernandez G. High-ω-6 seed oils and cardiovascular complications post-myocardial infarction in mice. J Mol Cell Cardiol. 2009;46(4):556–65. doi:10.1016/j.yjmcc.2008.12.004
18. Ramsden CE, Ringel A, Majchrzak-Hong SF, Taha AY, et al. ω-6 linoleic acid exacerbates Alzheimer’s pathology in transgenic APP/PS1 mice. J Clin Invest. 2012;122(6):2497–511. doi:10.1172/JCI58199
19. Sloop SR, Vickers KC, Kasuga D. Seed-oil formula augments septic mortality and macrophage activation neonatal piglets. Sci Rep. 2018;8(1):15723. doi:10.1038/s41598-018-34058-1
20. Thekkuttuparambil A, Sathishkumar S. High-linoleic canola diet accelerates early atherosclerotic lesions in ApoE-/- mice. J Clin Transl Endocrinol. 2024;35:100279. doi:10.1016/j.jcte.2023.100279
moonshot kimi k2 is a fantastic model to assist with research - use it via @PayPerQ - very cheap
i wonder how china is planning on censoring AI results. Seems like it breaks the great firewall.
bitchat is a drug dealers asynchronous drop point communication wet dream
Stacker News
The Gut Microbiota Mediates the Anti-Seizure Effects of the Ketogenic Diet \ stacker news ~HealthAndFitness
The ketogenic diet (KD) is used to treat refractory epilepsy, but the mechanisms underlying its neuroprotective effects remain unclear. Here, we sh...
make torrenting great again
-@ODELL
there is no housing shortage.
there are just outrageous housing prices.
US sends backdoored nvidia chips to china
China sends backdoored bitcoin asics to the US
seems like we sleep because of our mitochondria
https://www.science.org/content/blog-post/it-all-comes-down-mitochondria