if you can establish the child has Cerebral Folate Deficiency (CFD) or positive folate-receptor-α autoantibodies, leucovorin sounds like a promising therapy (for a subset of autism) https://www.mdpi.com/2075-4426/11/11/1141

the development of a fever is not a dysfunction of the human body, it is a natural process with a single goal: pathogen destruction

vaccine science is pretty suspect and vaccine zealots don't make criticizing it easy. the long term effects of the metals and adduces in vaccines are also basically unknown. however, if you take out the aluminum the injection causes no inflammation and goes from potentially not working to definitely not working.

if you ever wanted to do deep research on payments to physicians or hospitals from industry, this platform is a decent start

openpaymentsdata.cms.gov

CMS Open Payments

The official U.S. government website that houses data collected and published by Open Payments, a federally mandated program that collects informat...

my kids think the ATM is a money printer

High fructose corn syrup (HFCS) disrupts gut microbiome signaling through several interconnected mechanisms that alter microbial composition, metabolic pathways, and host-microbe communication: HFCS consumption directly induces gut dysbiosis, which refers to an imbalance in the gut microbial community that disrupts normal signaling between microbes and host cells . Unlike glucose, which is primarily metabolized systemically, fructose is predominantly metabolized in the small intestine where it interacts directly with the local microbiome. When consumed in excess (as is common with HFCS-sweetened beverages), fructose overwhelms the small intestine's metabolic capacity, allowing unabsorbed fructose to reach the colon where it creates an abnormal nutrient environment for gut bacteria. The excess fructose promotes the growth of pro-inflammatory bacterial species while suppressing beneficial bacteria that produce short-chain fatty acids (SCFAs), which are crucial signaling molecules for intestinal health . Fructose directly mediates innate immune responses and alters T-cell immunity, leading to increased inflammation. This occurs because fructose metabolism changes the metabolic environment in ways that favor pro-inflammatory immune cell differentiation. fructose promotes "leaky gut" through ethanol-inducible cytochrome P450-2E1-mediated oxidative and nitrative stress, compromising the gut barrier and allowing bacterial endotoxins to enter circulation . This triggers systemic inflammation and disrupts normal gut-liver axis signaling. The signaling disruption also affects lipid metabolism pathways. HFCS consumption increases lysophosphatidylcholine (LPC) species in serum by more than sevenfold, which cancer cells then consume to generate phosphatidylcholines for cell membrane production Signaling disruptions create vicious cycles - gut dysbiosis from HFCS promotes increased sugar preference through altered gut-brain signaling , leading to further HFCS consumption and worsening dysbiosis. https://www.nature.com/articles/s42255-025-01356-0 https://www.nature.com/articles/s44324-025-00066-1 https://www.nature.com/articles/s41575-025-01077-5 https://www.nature.com/articles/s41586-024-08258-3 https://www.nature.com/articles/s41564-024-01902-8

i really enjoy the flavor of coffee and in residency unfortunately got myself hooked on caffeine. as i have weened myself off to a cup a day I have substituted decaf. unfortunately conventional decaf is washed with methylene chloride or ethyl acetate to dissolve the caffeine. the swiss water method uses a water that is saturated with green coffee solubles except for caffeine which allows the caffeine to diffuse into the solution leaving behind a swollen caffeine free bean that can be dried and roasted. it is currently the only chemical free decaf method and happens at the Swiss Water plant in Vancouver BC.

I made this table for a family member who was trying to convince me the need to take a multivitamin. At worst you just urinate out the excess vitamins that are water soluble if you don't need them. However, I'd rather spend money on food than vitamins. It is very easy to get all of your micro-nutrients from animal based diets. Also easy as a carnivore as well but not necessary to be that restrictive.

we don't homeschool our kids but they probably learn most things at home. this site is an amazing worksheet collection for practicing math. since it is work, kids earn money for getting perfect scores

DadsWorksheets.com

DadsWorksheets.com - Free Printable Math Worksheets

Thousands of printable math worksheets for all grade levels, including an amazing array of alternative math fact practice and timed tests.

The value of intermittent fasting is probably grossly over exaggerated once you get down to a body fat percent of less than 15%

if you take a multivitamin make sure the where key B vitamins (primarily folate and vitamin B12) are pre-converted into their active, methylated forms—5-methyltetrahydrofolate (5-MTHF) for folate and methylcobalamin for B12—instead of using cheaper, synthetic precursors like folic acid or cyanocobalamin

the interesting result of so many people taking GLP-1 agonists is the exposure of diseases that improve with weight loss. recently there are reports of psoriasis improving and i suspect we will see the mainstream finally acknowledge that most if not all autoimmune conditions have an origin with metabolic dysfunction resulting from obesity. adipose cells are extremely hormonally active and play a role in many "untreatable" chronic diseases this is probably why the carnivore diet helps so many because it often results in substantial weight loss (at least initially).

keep your shoulder mobility as you do a lot of pushups by doing them hindu style

The gut-brain axis is implicated in the pathophysiology of numerous mental health disorders, such as depression, anxiety, and schizophrenia. Our intestines have more serotonin and dopamine receptors than our brain.

The correlation between gut microbiota and both neurotransmitters and mental disorders: A narrative review - PMC

The gastrointestinal tract is embedded with microorganisms of numerous genera, referred to as gut microbiota. Gut microbiota has multiple effects o...

happiness is an inside job

weighted pull ups over time have put too much stress on my wrist and metacarpals. using these pull up hooks have solved those issues so i can do 50lb weighted pull ups x5 without any injuries.

Amazon.com: Workout Gloves Men

Shop men's fitness gloves with ergonomic design and enhanced grip technology. Protect your hands while maintaining dexterity during weight lifting ...

most of the time I find that in the afternoon, especially after doing a workout in the morning, my body craves a snack, but it's really craving solutes like sodium chlorine, magnesium and calcium. Drinking a sugar free electrolyte solution can stave off any further cravings until dinner. Also if you drink caffeine you have increased urination of your electrolytes.

The mitochondrial-stem cell connection (MSCC) theory suggests that cancer originates from chronic oxidative phosphorylation (OxPhos) insufficiency in stem cells. This OxPhos insufficiency leads to the formation of cancer stem cells (CSCs) and abnormal energy metabolism, ultimately resulting in malignancy.

ISOM

Targeting the Mitochondrial-Stem Cell Connection in Cancer Treatment: A Hybrid Orthomolecular Protocol

. Introduction Many theories exist regarding the origin of cancer, namely the metabolic theory (Seyfried & Chinopoulos, 2021), the somatic mut...

why is the "outside aisles of the grocery store" the good part and the "inside aisles" bad? because the outside edges are where the refrigeration units are. fresh single ingredient foods are not preserved and need to be quickly cycled through the store.

one of the best things you can do as a parent is prevent at all costs unsupervised youtube. unless they are using it for research with your help, youtube is an algorithmic cesspool