in medicine, there is a saying: "don't just do something, stand there" often observing, waiting, being patient and staying calm is the best and hardest course of action there may be a time to act, but that time does not always have to be now

don't fear fructose! as long as you are not consuming excessive calories compared to your energy demands, fructose does not produce harmful effects. however, excess fructose above your caloric needs does get converted to bacterial endotoxins in the gut which damages multiple organs, specifically the liver so the most important point in creating health, is balancing energy demands with the beneficial effects of carbohydrates

PubMed

The effects of fructose intake on serum uric acid vary among controlled dietary trials - PubMed

Hyperuricemia is linked to gout and features of metabolic syndrome. There is concern that dietary fructose may increase uric acid concentrations. T...

the average highly paid professional is still clueless to the superhuman power that LLMs give to a motivated employee. need to create the skeleton of an research protocol: BAM! need to review an unnecessary long document: BAM! need to write R code to analyze a dataset: BAM! need to generate a schedule for multiple shifts times while taking into account vacation requests: BAM! this is only the beginning. one person with digital help can centralize 10+ jobs and have more time for dog walks

my kids have never had a bowl of cereal. they have eaten cereal even terrible ones but always dry and always in the setting of it being like "halloween candy". even the concept of cereal for breakfast grosses them out since they are so used to homemade pancakes, muffins, eggs, bacon, sausage and filling food for breakfast. if you start kids young with delicious foods and explain to them why we eat different breakfast from their friends they don't fight you and embrace good eating. we tried saying "you can't have fruit loops" but it wasn't as effective as me letting them have fruit loops when on vacation and showing them that 2 hours later they were hungry and moody for them to understand our reasoning. talking to kids like they are adults instead of just saying "no" is never as effective as helping the learn from experience, especially bad experiences.

High Protein Efficiency Ratio —> Supports Tissue Growth • High Net Protein Utilization/ High Biologic Value —> Efficiently used by the body • High Protein Digestibility Corrected Amino Acid Score —> Contains the needed amino acids

PubMed

The effects of dairy and dairy derivatives on the gut microbiota: a systematic literature review - PubMed

The effects of dairy and dairy-derived products on the human gut microbiota remains understudied. A systematic literature search was conducted usin...

i unplugged from all news several years ago. when at work i always find out about the newest thing and getting information by word of mouth is a wonderful filter. i spend a lot of time reading books, scientific papers and using computers and technology but have become allergic to news alerts, latest thing podcasts, and twitter like feeds. mostly on nostr I post and ghost and prefer content that is first principled and scientific or has stood the test of 5+ years of time.

almost all of the academic busy work that faculty deal with such as grant writing, paper writing, yearly performance review and peer review is made 1000 times easier with large language models and moonshot. K2 is a game changer.

once you get on a glp-1 you will be on it for life unless you also make significant lifestyle modifications. and when you get off it the weight will come back faster than the losses https://www.bmj.com/content/392/bmj-2025-085304

when you play a greyscale game, your mind activates to fill in the color. it is also easy to put it down because it i less "addictive" due to lower visual stimulation. my kids love puzzle games on @daylightco and it is fun to watch them team up to solve them.

embrace boredom. sometimes it is exactly what your brain needs

our need for sleep and the importance of long amounts of uninterrupted sleep may be driven by our mitochondria During wakefulness, your neurons fire constantly, consuming enormous amounts of ATP. This drives the electron transport chain (ETC) at maximum capacity, which creates two critical problems: energy depletion and oxidation 1. Energy depletion: ATP gets hydrolyzed to ADP and AMP. The resulting low ATP/ADP ratio is a direct metabolic stress signal. Adenosine (formed from these breakdown products) accumulates and is a well-established sleep pressure molecule. When we sleep neuronal activity decreases, allowing the electron transport chain to operate at lower capacity and reducing oxidation production and allow the reduction (opposite of oxidation) to catch up the mitochondrial quality control mechanisms (mitophagy, biogenesis, fission/fusion dynamics) actively repair damage and replace dysfunctional mitochondria at a greater rate during sleep. https://www.science.org/content/blog-post/it-all-comes-down-mitochondria

it is widely accepted in veterinary medicine that many canine skin disorders are as a result of zinc deficiency and poor gut health. after treating any topic fungal or bacterial infections, most vets will suggest a probiotic supplemented with minerals to maintain high quality fur grown and skin health. very rarely do we see this offered in human medicine but it in fact clears up many skin issues though to be "autoimmune" https://link.springer.com/article/10.1007/s40257-019-00484-0 https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1600-0625.2009.00932.x

the basis of modern virology

in medicine it is always enlightening to find natural controls. the Amish population serve as a human control --- but from a genetic standpoint, chimps serve as a control as well. chimps in captivity have an approximate 2% cancer incidence yet share 99% similar genetics as humans. either that 1% genetic difference accounts for all of the increased malignancies in humans or humans have done something to themselves that create all of the malignancies that plague our modern health. many will say that we get cancers because we live longer but captive chimpanzees live twice as long (15+ years more) than wild chimps so their lack of cancer is eye opening.

Comparative analysis of cancer genes in the human and chimpanzee genomes - PMC

Cancer is a major medical problem in modern societies. However, the incidence of this disease in non-human primates is very low. To study whether g...

People feel invigorated after an ice bath because cold receptors in your skin trigger sympathetic nervous system activation. Plasma norepinephrine and dopamine spike within seconds since your physiologic response is to "get out as fast as possible" Then your pituitary gland pumps out beta-endorphins to bind opioid receptors to counteract the pain of the cold exposure (just like a runners high) Vasoconstriction shunts blood to your core. When you exit, peripheral vasodilation creates a surge of oxygenated blood to your muscles and brain. Your cognitive override of all these systems trying to get you out of the bath is fed by a later dopamine reward and your normal warm environment then feels like a luxury.

the concept of the "6 month dental health check and cleaning" is largely a construct of dental insurance coverage. it was created as part of a pepsodent tooth paste advertisement in the 1950s and then solidified by dental insurance. when you sign up for a dental plan you are essentially prepaying for the teeth "cleaning". this is why if you are self pay they rarely ever call you to get your teeth cleaning since they know you won't want to pay for it if you haven't already prepaid via your employer plan. there has never been any scientific backing to visiting a dentist twice a year. is it a good idea...maybe but also is like visiting a mechanic when you don't have an issue...

this viral control study is the best modern one that I have read. They purposely inoculated people with H3N2 and then compared the transmission in masks vs no mask and unfortunately only one transmission event occurred. It was so hard to get people sick with H3N2 even when being quaranteened in the same room that they concluded that it must be the ventilation rather than then possibility that something might be wrong with the theory of contagion. https://files.ostermayer.co/contagion/ppat.1008704.pdf

not sure how function health gets their labs down so cheap but it is better for most people to get all their labs from them and then just take the results to their doctor for review if they have questions

Function Dashboard

It’s time you own your health. Function starts with 160+ lab tests and personalized protocols for instant action. Tracked over time in one secure...

i have helped run a wiki for emergency medicine since i was a resident and of all the things that I have done in medicine, bringing open access medical knowledge to clinicians around the world has brought me the greatest joy. No paywalls. No fees. Available at the bedside globally. at wikem.org we have created the greatest open medical textbook for clinicians. we are now using LLMs to translate every page into spanish at a speed i could have never imagined

right now healthcare practices make money when people get sick, imagine a healthcare practice that you pay for that keeps you healthy and sick visits are free. the physician has a financial interest to keep your healthy since the less sick you are the less time they need to spend with you in the office and the less time the patient has to take time off of work to see the doctor.